Article
Imaging atherosclerosis in rheumatoid arthritis: evidence for increased prevalence, altered phenotype and a link between systemic and localised plaque inflammation.
Scientific reports - 11 Apr 2017
Skeoch S, Cristinacce P L Hubbard, Williams H, Pemberton P, Xu D, Sun J, James J, Yuan C, Hatsukami T, Hockings P D, Alexander M Y, Waterton J C, Bruce I N
Abstract excerpt
In rheumatoid arthritis (RA), chronic inflammation is thought to drive increased cardiovascular risk through accelerated atherosclerosis. It may also lead to a more high-risk plaque phenotype. We sought to investigate carotid plaque phenotype in RA patients using Dynamic Contrast-Enhanced MRI (DCE-MRI) and Fludeoxyglucose Positron Emission Tomography(FDG-PET). In this pilot study, RA patients and age/sex-matched...
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