Computerized mathematical model of M. leprae population dynamics during multiple drug therapy.

Article

Computerized mathematical model of M. leprae population dynamics during multiple drug therapy.

Indian journal of leprosy - 1 Jan 2000

Almeida J G, Chacko C J

Abstract excerpt

A computerized mathematical model of M. leprae populations during multiple drug therapy (MDT) was constructed. Relevant published information available to date was fed into it, and reasoned assumptions were made. From the model, it seems likely that MDT steadily selects bacteria resistant to the...

Topics

Drug Resistance, Microbial
Drug Therapy, Combination
Humans
Leprosy
Mathematics
Models, Biological
Mutation
Mycobacterium leprae
Software

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