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Inflammation, mitochondrial and lysosomal dysfunction as key players in rheumatoid arthritis?

14 Aug 2024

Abstract excerpt

Rheumatoid arthritis (RA) is an inflammatory joint disease characterized by persistent synovitis and inflammation. The exact mechanism of mitochondrial function in the presence of inflammation and dysregulation of autophagic processes in the pathogenesis of RA is still unclear. The aim of our study is to determine mitochondrial function, gene and protein levels of biomolecules related to inflammation (YKL-40) and...

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PMID: 39146785
DOI: 10.1016/j.intimp.2024.112919

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