Article
Association between MAPK and PI3K/Akt signaling pathway-related gene polymorphisms and migraine.
Molecular genetics & genomic medicine - 1 Aug 2024
Wang Mingxue, Gu Yujia, Meng Shuhan, Kang Lixin, Yang Jing, Sun Degang, Liu Yuxing, Wan Ze, Shan Yi, Xue Dongjie, Su Chang, Li Shufen, RanYan, Liu Yu, Pan Yonghui, Zhao Yashuang
Abstract excerpt
BACKGROUND: The causes of migraine remain unclear. Evidence suggests that the MAPK and PI3K/Akt signaling pathways play a role in migraine pathogenesis. However, studies on genetic polymorphisms in the two pathways associated with migraine are still limited. METHODS: This study included 226 migraineurs and 452 age- and sex-matched nonmigraine control individuals. Genotyping of 31 Single Nucleotide Polymorphisms...
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