Article
BDNF and CGRP interaction: implications in migraine susceptibility.
Cephalalgia : an international journal of headache - 1 Nov 2010
Lemos Carolina, Mendonça Denisa, Pereira-Monteiro José, Barros José, Sequeiros Jorge, Alonso Isabel, Sousa Alda
Abstract excerpt
OBJECTIVES: Migraine pathophysiology involves several pathways. Our aims were to explore a possible role of the brain-derived neurotrophic factor gene (BDNF) in migraine susceptibility; to study, for the first time, the calcitonin gene-related peptide gene (CGRP); and a possible interaction between the two. METHODS: Using a case-control approach, four tagging single nucleotide polymorphisms (SNPs) (rs7124442,...
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