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Guidelines for minimal information on cellular senescence experimentation in vivo

1 Aug 2024

Abstract excerpt

Cellular senescence is a cell fate triggered in response to stress and is characterized by stable cell-cycle arrest and a hypersecretory state. It has diverse biological roles, ranging from tissue repair to chronic disease. The development of new tools to study senescence in vivo has paved the way for uncovering its physiological and pathological roles and testing senescent cells as a therapeutic target. However,...

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PMID: 39121846
DOI: 10.1016/j.cell.2024.05.059

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