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Article

A large-scale in vivo screen to investigate the roles of human genes in Drosophila melanogaster.

G3 (Bethesda, Md.) - 7 Oct 2024

Avila Ashley, Paculis Lily, Tascon Roxana Gonzalez, Ramos Belen, Jia Dongyu

Abstract excerpt

Understanding the signaling pathways in which genes participate is essential for discovering the etiology of diseases in humans. The model organism, Drosophila melanogaster, has been crucial in understanding the signaling pathways in humans, given the evolutionary conservation of a significant number of genes between the two species. Genetic screens using Drosophila are a useful way of testing large number of...

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PMID: 39119785
DOI: 10.1093/g3journal/jkae188
PMCID: PMC11457089

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