Article
Using Drosophila melanogaster to uncover human disease gene function and potential drug target proteins.
Expert opinion on therapeutic targets - 1 Jun 2002
Reiter Lawrence T, Bier Ethan
Abstract excerpt
The fruit fly Drosophila melanogaster is a powerful genetic model organism, which has been instrumental in the determination of essential developmental and neurological pathways conserved from invertebrates to humans. With the completion of both the human and Drosophila genomes, the revelation that we are more similar to this simple organism than previously suspected was realised. 75% of human genetic disease...
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