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Article

Identification of potential therapeutic targets for skin cutaneous melanoma on the basic of transcriptomics.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) - 1 Aug 2024

Shi Fengling, Li Tao, Shi Huiling, Wei Yushan, Wang Juan, Liu Canyu, Liang Ruirong

Abstract excerpt

BACKGROUND: Advanced skin cutaneous melanoma (SKCM) is responsible for the majority of skin cancer-related deaths. Apart from the rare BRAF V600F mutation, which can be targeted with specific drugs, there are currently no other novel effective therapeutic targets. METHODS: We used SMR analysis with cis-expressed quantitative trait locus (cis-eQTL) as the exposure variable and SKCM as the outcome variable to...

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Identifiers

PMID: 39113615
DOI: 10.1111/srt.13916
PMCID: PMC11306917

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