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Article

Recurrence of fusocellular subtype GIST with SDHB mutation: A case of SDHB-loss and therapeutic challenges.

Journal of surgical oncology - 1 Sept 2024

da Silva Gomes Samuel, Oliveira Carolina S, Furtado Thiago de Almeida, Melo Lara M, Dos Santos Sara G, Braga Renata S N, Martins Eduarda M T G, Gomes João P Dos Santos

Abstract excerpt

Gastrointestinal stromal tumors (GISTs) are sarcomas affecting the stomach and small intestine, with a rare subtype characterized by succinate dehydrogenase B (SDHB)-loss posing significant diagnostic and therapeutic challenges. A 62-year-old man with weight loss and abdominal pain was diagnosed with a gastric GIST showing SDHB-loss. Initial treatment with Imatinib reduced the tumor size, but surgery revealed no...

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Identifiers

PMID: 39099211
DOI: 10.1002/jso.27727

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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