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A chimeric vaccine derived from Australian genotype IV Japanese encephalitis virus protects mice from lethal challenge

31 Jul 2024

Abstract excerpt

Abstract In 2022, a genotype IV (GIV) strain of Japanese encephalitis virus (JEV) caused an unprecedented and widespread outbreak of disease in pigs and humans in Australia. As no veterinary vaccines against JEV are approved in Australia and all current approved human and veterinary vaccines are derived from genotype (G) III JEV strains, we used the recently described insect-specific Binjari virus (BinJV)...

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PMID: 39085247
DOI: 10.1038/s41541-024-00903-2

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