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Article

Single nucleotide polymorphism of Notch1 gene rs3124599 allele is associated with the severity of CVA6-related HFMD in the Chinese Han population.

BMC infectious diseases - 29 Jul 2024

Li Zijie, Ji Wangquan, Dai Bowen, Chen Shouhang, Wang Fang, Duan Guangcai, Jin Yuefei

Abstract excerpt

BACKGROUND: There is evidence suggesting that Notch1 signaling pathway contributes to the development of hand, foot, and mouth disease (HFMD); however, the role of Notch1 gene polymorphisms in the severity of coxsackievirus A6 (CVA6)-related HFMD remains unclear. This study aimed to investigate the correlation between Notch1 gene polymorphisms and the severity of CVA6-related HFMD. METHODS: A total of 196...

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Identifiers

PMID: 39075371
DOI: 10.1186/s12879-024-09640-2
PMCID: PMC11287834

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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