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Article

Genome-wide association study identifies TPH2 variant as a novel locus for severe CV-A6-associated hand, foot, and mouth disease in Han Chinese.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Sept 2020

Meng Yu, Xiong Tiantian, Zhao Rongxian, Liu Jian, Yu Guangqing, Xiao Jinrong, Wang Ke, Wu Taishun, Fu Wenshan, Guo Huan, Huang Jiao, Wei Sheng

Abstract excerpt

BACKGROUND: Little is known about the association between genetic susceptibility and the severity of hand, foot, and mouth disease (HFMD) infected with coxsackievirus A6 (CV-A6). METHODS: Three hundred and sixty-four CV-A6 HFMD patients were enrolled, including 115 severe and 249 mild patients. A genome-wide association study (GWAS) was performed involving eight DNA pools of 115 severe and 115 mild CV-A6 HFMD...

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PMID: 32634583
DOI: 10.1016/j.ijid.2020.06.104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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