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In vivo monitoring of active subretinal fibrosis in mice using collagen hybridizing peptides

26 Jul 2024

Abstract excerpt

Subretinal fibrosis is associated with worse visual outcomes in patients with neovascular age-related macular degeneration. As there is a lack of optimal biomarkers and no method that directly detects collagen in the back of the eye, novel tools that monitor fibrosis-related changes in neovascular age-related macular degeneration are needed. Here, using two mouse models (the laser-induced choroidal...

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PMID: 39060633
DOI: 10.1038/s41684-024-01408-0

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