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Targeted whole-genome recovery of single viral species in a complex environmental sample

25 Jul 2024

Abstract excerpt

Characterizing unknown viruses is essential for understanding viral ecology and preparing against viral outbreaks. Recovering complete genome sequences from environmental samples remains computationally challenging using metagenomics, especially for low-abundance species with uneven coverage. We present an experimental method for reliably recovering complete viral genomes from complex environmental samples....

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PMID: 39052829
DOI: 10.1073/pnas.2404727121

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