Article

Prospective metagenomic sequencing of wastewater across the United States yields robust viral enrichment and concordance with digital PCR measurements

2026-05-08

Abstract excerpt

Metagenomic sequencing is increasingly applied to wastewater to characterize the diversity, dynamics, and relative abundance of human and animal viruses. Among these sequencing approaches are those that enrich viral nucleic acids from the wastewater matrix, aiming to increase the viral read fraction for analysis. However, the feasibility of scaling targeted viral sequencing to diverse sewersheds across large geogr...

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Literature Corpus work: a848095b-fd6d-57d7-87a5-2309c5fc8524
DOI: 10.64898/2026.05.07.26352651

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