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Whole-genome sequencing of adenovirus 41 directly from wastewater using nested overlapping PCR and MinION

5 Aug 2026

Abstract excerpt

ABSTRACT Human adenovirus F41 (HAdV-F41) is one of the leading causes of children’s acute gastroenteritis and was recently linked to an outbreak of severe acute hepatitis of unknown etiology among children during 2021 to 2022. While most evidence is based on clinical data, wastewater-based epidemiology offers a community-level approach to monitoring circulating strains and enhancing outbreak preparedness. In this...

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PMID: 42554480
DOI: 10.1128/spectrum.00471-26

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