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Article

Unraveling clinical outcomes of long-term cART treatment in HIV-1 patients with or without the Brazilian GWGR motif in the V3 loop.

Revista do Instituto de Medicina Tropical de Sao Paulo - 1 Jan 2024

Folgosi Victor Ângelo, Komninakis Shirley Vasconcelos, Lopes Luciano, Monteiro Mariana Amélia, Assone Tatiane, Fonseca Luiz Augusto Marcondes, Domingues Wilson, Leite Junior Pedro Domingos, Victor Jefferson Russo, Casseb Jorge

Abstract excerpt

The presence of genetic mutations in HIV poses a significant challenge, potentially leading to antiretroviral resistance and hampering therapeutic development. The Brazilian population has presented variations in the HIV envelope V3 loop gene, especially the GWGR motif. This motif has been linked to reduced transmission potential and slower CD4+ T cell decline. This study aimed to assess clinical outcomes in...

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Identifiers

PMID: 39052025
DOI: 10.1590/S1678-9946202466038
PMCID: PMC11251515

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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