Article
CTHRC1 is associated with BRAF(V600E) mutation and correlates with prognosis, immune cell infiltration, and drug resistance in colon cancer, thyroid cancer, and melanoma.
Biomolecules & biomedicine - 11 Dec 2024
Zhang Rumeng, Wang Zhihao, Wang Huan, Li Lin, Dong Lin, Ding Lin, Li Qiushuang, Zhu Linyan, Zhang Tiantian, Zhu Yong, Ding Keshuo
Abstract excerpt
Colon cancer, thyroid cancer, and melanoma are common malignant tumors that seriously threaten human health globally. The B-Raf proto-oncogene, serine/threonine kinase (BRAF)(V600E) mutation is an important driver gene mutation in these cancer types. In this study, we identified that collagen triple helix repeat containing 1 (CTHRC1) expression was associated with the BRAF(V600E) mutation in colon cancer, thyroid...
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