Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of blood metabolites in mediating the effect of gut microbiome on the mutated-RAS/BRAF metastatic colorectal cancer-specific survival.

International journal of colorectal disease - 24 Jul 2024

Xiang Yaoxian, Zhang Chan, Wang Jing, Cheng Yurong, Wang Kangjie, Wang Li, Tong Yingying, Yan Dong

Abstract excerpt

BACKGROUND: Recent studies have linked alterations in the gut microbiome and metabolic disruptions to the invasive behavior and metastasis of colorectal cancer (CRC), thus affecting patient prognosis. However, the specific relationship among gut microbiome, metabolite profiles, and mutated-RAS/BRAF metastatic colorectal cancer (M-mCRC) remains unclear. Furthermore, the potential mechanisms and prognostic...

Topics

Join the communities discussing this publication.

Colorectal Neoplasms
Gastrointestinal Microbiome
Mendelian Randomization Analysis
Metabolome
Neoplasm Metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins B-raf

Survival Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 39046546
DOI: 10.1007/s00384-024-04686-9
PMCID: PMC11269474

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of blood metabolites in mediating the effect of gut microbiome on the mutated-RAS/BRAF metastatic colorectal cancer-specific survival.PMID 39046546Read ↗

Metabolomic analysis reveals key changes in amino acid metabolism in colorectal cancer patientsSemantic proximity Read ↗

Systematic investigation of genetically determined plasma and urinary metabolites to discover potential interventional targets for colorectal cancer.Semantic proximity Read ↗

Gut microbiome-metabolites axis: A friend or foe to colorectal cancer progressionSemantic proximity Read ↗

Shaping the future of gastrointestinal cancers through metabolic interactions with host gut microbiotaSemantic proximity Read ↗

RAS mutations and colorectal cancer metabolism: a metabolomic analysis of tissue samples.Semantic proximity Read ↗

A Review of Gut Microbiota‐Derived Metabolites in Tumor Progression and Cancer TherapySemantic proximity Read ↗

Microbiome and metabolic features of tissues and feces reveal diagnostic biomarkers for colorectal cancerSemantic proximity Read ↗

Genetically predicted 486 blood metabolites in relation to risk of colorectal cancer: A Mendelian randomization study.Semantic proximity Read ↗

Metabolomic markers of colorectal tumor with different clinicopathological featuresSemantic proximity Read ↗

Identification of Gut Microbiota Profile Associated with Colorectal Cancer in Saudi PopulationSemantic proximity Read ↗

Integrated analysis of the faecal metagenome and serum metabolome reveals the role of gut microbiome-associated metabolites in the detection of colorectal cancer and adenomaSemantic proximity Read ↗

Colorectal Cancer: Pathogenesis and Targeted TherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.