Article
TP53 mutations in urothelial carcinoma: not all one and the same†.
The Journal of pathology - 1 Oct 2024
Barr Alexis R, Burley Amy, Wilkins Anna
Abstract excerpt
Systemic therapy options for urothelial carcinoma have expanded in recent years, with both immunotherapy and cytotoxic chemotherapy being widely available. However, we lack biomarkers to select which drug is likely to work best in individual patients. A new article in this journal by Jin, Xu, Su, et al reports that disruptive versus non-disruptive TP53 mutations may guide these personalised therapy choices....
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