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An integrated pan-cancer assessment of prognosis, immune infiltration, and immunotherapy response for B7 family using multi-omics data.

Life sciences - 15 Sept 2024

Zhao Gangjian, Li Peng, Suo Yong, Li Chenyun, Yang Shaobo, Zhang Zhe, Wu Zhouliang, Shen Chong, Hu Hailong

Abstract excerpt

AIMS: B7 molecules (B7s) are crucial synergistic signals for effective immune surveillance against tumor cells. While previous studies have explored the association between the B7 family and cancer, most have been limited to specific genes or cancer subtypes. MAIN METHODS: Our study utilized multi-omics data to investigate potential correlations between B7s expression (B7s exp.) and prognosis, clinicopathological...

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Biomarkers, Tumor
DNA Copy Number Variations
Gene Expression Regulation, Neoplastic
Immunotherapy
Lymphocytes, Tumor-Infiltrating

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Microenvironment

Urinary Bladder Neoplasms

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PMID: 39034028
DOI: 10.1016/j.lfs.2024.122919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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