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Osteostaticytes: A novel osteoclast subset couples bone resorption and bone formation

24 Jun 2024

Abstract excerpt

Osteomyelitis (OM) is an inflammatory condition of bone characterized by cortical bone devascularization and necrosis. Dysregulation of bone remodelling is triggered by OM. Bone remodelling is precisely coordinated by bone resorption and formation via a reversal phase. However, the cellular and molecular mechanisms underlying bone remodelling failure after osteomyelitis remain elusive. To elucidate the cellular...

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PMID: 39027343
DOI: 10.1016/j.jot.2024.06.010

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