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Nanopore-based targeted next-generation sequencing of tissue samples for tuberculosis diagnosis

3 Jul 2024

Abstract excerpt

Objective Diagnosing tuberculosis (TB) can be particularly challenging in the absence of sputum for pulmonary tuberculosis cases and extrapulmonary TB (EPTB). This study evaluated the utility of nanopore-based targeted next-generation sequencing (tNGS) for diagnosing TB in tissue samples, and compared its efficacy with other established diagnostic methods. Methods A total of 110 tissue samples from clinical cases...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39027106
DOI: 10.3389/fmicb.2024.1403619

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