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Article

The levels of circulating cytokines and risk of neuromyelitis optica spectrum disorder: a Mendelian randomization study.

Frontiers in immunology - 1 Jan 2024

Ma Xue, Wang Yao, Chen Xin, Guo Jun

Abstract excerpt

Background: Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory autoimmune disease affecting the central nervous system (CNS). NMOSD pathogenesis involves systemic inflammation. However, a causal relationship between circulating cytokine levels and NMOSD remains unclear. Methods: Mendelian randomization (MR) approaches were used to investigate the potential association between genetically determined...

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Identifiers

PMID: 39011048
DOI: 10.3389/fimmu.2024.1418309
PMCID: PMC11246864

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