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Article

Post-implantation analysis of genomic variations in the progeny from developing fetus to birth.

Human genomics - 15 Jul 2024

Zheng Yingming, Lin Chuanping, Wang Wen-Jing, Wang Liya, Qian Yeqing, Mao Luna, Li Baohua, Lou Lijun, Mao Yuchan, Li Na, Zheng Jiayong, Jiang Nan, He Chaying, Wang Qijing, Zhou Qing, Chen Fang, Jin Fan

Abstract excerpt

The analysis of genomic variations in offspring after implantation has been infrequently studied. In this study, we aim to investigate the extent of de novo mutations in humans from developing fetus to birth. Using high-depth whole-genome sequencing, 443 parent-offspring trios were studied to compare the results of de novo mutations (DNMs) between different groups. The focus was on fetuses and newborns, with DNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39010135
DOI: 10.1186/s40246-024-00634-4
PMCID: PMC11247737

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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