Article

Whole-exome sequencing analysis on products of conception: A cohort study to evaluate clinical utility and genetic etiology for pregnancy loss

2020-07-20

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> Pregnancy loss ranging from spontaneous abortion (SAB) to stillbirth can result from monogenic causes of Mendelian inheritance. This study evaluated the clinical application of whole exome sequencing (WES) in identifying the genetic etiology for pregnancy loss. <h4>Methods</h4> A cohort of 102 specimens from products of conception (POC) with normal karyotype and absence of pathog...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 26939ca9-6a8c-590b-a8ed-31e73d3bec94
DOI: 10.1101/2020.07.19.20150144

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Whole-exome sequencing analysis on products of conception: A cohort study to evaluate clinical utility and genetic etiology for pregnancy lossDOI 10.1101/2020.07.19.20150144Read

Exome sequencing analysis on products of conception: a cohort study to evaluate clinical utility and genetic etiology for pregnancy lossSemantic proximity Read

Whole-genome sequencing analysis in families with recurrent pregnancy loss: A pilot studySemantic proximity Read

Genetic analysis of pregnancy loss and fetal structural anomalies by whole exome sequencingSemantic proximity Read

Whole-genome sequencing analysis in families with recurrent pregnancy loss: A pilot studySemantic proximity Read

Whole‑exome sequencing analysis of products of conception identifies novel mutations associated with missed abortionSemantic proximity Read

Discovery of Pathogenic Variants Associated with Idiopathic Recurrent Pregnancy Loss Using Whole-Exome Sequencing.Semantic proximity Read

The Human Intolerome: a curated database to prioritize genomic variants in stillbirth, pregnancy loss, and neonatal deathSemantic proximity Read

PLoV: a comprehensive database of genetic variants leading to pregnancy loss.Semantic proximity Read

Whole-exome Sequencing in deceased fetuses with ultrasound anomalies: A Retrospective AnalysisSemantic proximity Read

Trio-whole-exome sequencing and preimplantation genetic diagnosis for unexplained recurrent fetal malformations.Semantic proximity Read

Identification of genetic polymorphisms in unexplained recurrent spontaneous abortion based on whole exome sequencingSemantic proximity Read

Diagnostic yield and clinical impact of prenatal whole exome sequencing (WES) - four-year single center experience.Semantic proximity Read