Article
Microstructural characterization of multiple sclerosis lesion phenotypes using multiparametric longitudinal analysis.
Journal of neurology - 1 Sept 2024
Ravano Veronica, Andelova Michaela, Piredda Gian Franco, Sommer Stefan, Caneschi Samuele, Roccaro Lucia, Krasensky Jan, Kudrna Matej, Uher Tomas, Corredor-Jerez Ricardo A, Disselhorst Jonathan A, Maréchal Bénédicte, Hilbert Tom, Thiran Jean-Philippe, Richiardi Jonas, Horakova Dana, Vaneckova Manuela, Kober Tobias
Abstract excerpt
BACKGROUND AND OBJECTIVES: In multiple sclerosis (MS), slowly expanding lesions were shown to be associated with worse disability and prognosis. Their timely detection from cross-sectional data at early disease stages could be clinically relevant to inform treatment planning. Here, we propose to use multiparametric, quantitative MRI to allow a better cross-sectional characterization of lesions with different...
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