Article
Activation and Autoinhibition Mechanisms of NLR Immune Receptor Pi36 in Rice.
International journal of molecular sciences - 2 Jul 2024
Yang Yang, Tan Liu, Xu Xingzhe, Tang Qiaoyi, Wang Ji, Xing Shiyue, Wang Rui, Zou Ting, Wang Shiquan, Zhu Jun, Li Shuangcheng, Liang Yueyang, Deng Qiming, Li Ping
Abstract excerpt
Nucleotide-binding and leucine-rich repeat receptors (NLRs) are the most important and largest class of immune receptors in plants. The Pi36 gene encodes a canonical CC-NBS-LRR protein that confers resistance to rice blast fungal infections. Here, we show that the CC domain of Pi36 plays a role in cell death induction. Furthermore, self-association is required for the CC domain-mediated cell death, and the...
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