Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cellular senescence and metabolic reprogramming: Unraveling the intricate crosstalk in the immunosuppressive tumor microenvironment

12 Jul 2024

Abstract excerpt

The intrinsic oncogenic mechanisms and properties of the tumor microenvironment (TME) have been extensively investigated. Primary features of the TME include metabolic reprogramming, hypoxia, chronic inflammation, and tumor immunosuppression. Previous studies suggest that senescence-associated secretory phenotypes that mediate intercellular information exchange play a role in the dynamic evolution of the TME....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Immune cells in cancer
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38997794
DOI: 10.1002/cac2.12591

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cellular senescence and metabolic reprogramming: Unraveling the intricate crosstalk in the immunosuppressive tumor microenvironmentPMID 38997794Read ↗

T-cell Senescence in the Tumor MicroenvironmentSemantic proximity Read ↗

Senescence and tumor suppressionSemantic proximity Read ↗

Senescence and Immunoregulation in the Tumor MicroenvironmentSemantic proximity Read ↗

Harnessing the interaction between redox signaling and senescence to restrain tumor drug resistanceSemantic proximity Read ↗

Regulation of cellular senescence in tumor progression and therapeutic targeting: mechanisms and pathwaysSemantic proximity Read ↗

Polarization of Tumor Cells and Tumor‐Associated Macrophages: Molecular Mechanisms and Therapeutic TargetsSemantic proximity Read ↗

Overcoming the senescence-associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer.Semantic proximity Read ↗

Senescence and the tumor-immune landscape: Implications for cancer immunotherapy.Semantic proximity Read ↗

Bone Marrow Senescence and the Microenvironment of Hematological MalignanciesSemantic proximity Read ↗

The epigenetic landscape of tumor-associated macrophages: orchestrating immune evasion in the tumor microenvironmentSemantic proximity Read ↗

Oxidative stress and cellular senescence: Roles in tumor progression and therapeutic opportunitiesSemantic proximity Read ↗

Cellular senescence and the tumour microenvironment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.