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Associations between APOE genotypes, urine 8-isoprostane and blood trace elements in middle-aged mothers (CROME study).

Environment international - 1 Nov 2024

France Štiglic Alenka, Stajnko Anja, Sešek Briški Alenka, Snoj Tratnik Janja, Mazej Darja, Jerin Aleš, Skitek Milan, Horvat Milena, Marc Janja, Falnoga Ingrid

Abstract excerpt

BACKGROUND: There is almost no data on the combined associations between apolipoprotein E gene (APOE) genotypes, trace elements (TEs), and lipid peroxidation in vivo. The aim of our study was to evaluate the association between APOE genotypes and TE levels in blood (B-TEs) and erythrocytes (E-TEs), and 8-isoprostane in urine (U-8-isoprostane) in women with low exposure to potentially toxic TEs and with adequate...

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PMID: 39447471
DOI: 10.1016/j.envint.2024.109034

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