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Article

HIV-1 diversity and pre-treatment drug resistance in the era of integrase inhibitor among newly diagnosed ART-naïve adult patients in Luanda, Angola.

Scientific reports - 10 Jul 2024

Sebastião Cruz S, Abecasis Ana B, Jandondo Domingos, Sebastião Joana M K, Vigário João, Comandante Felícia, Pingarilho Marta, Pocongo Bárbara, Cassinela Edson, Gonçalves Fátima, Gomes Perpétua, Giovanetti Marta, Francisco Ngiambudulu M, Sacomboio Euclides, Brito Miguel, Neto de Vasconcelos Jocelyne, Morais Joana, Pimentel Victor

Abstract excerpt

The surveillance of drug resistance in the HIV-1 naïve population remains critical to optimizing the effectiveness of antiretroviral therapy (ART), mainly in the era of integrase strand transfer inhibitor (INSTI) regimens. Currently, there is no data regarding resistance to INSTI in Angola since Dolutegravir-DTG was included in the first-line ART regimen. Herein, we investigated the HIV-1 genetic diversity and...

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Angola
Cross-Sectional Studies
Drug Resistance, Viral
High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HIV Integrase Inhibitors

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PMID: 38987263
DOI: 10.1038/s41598-024-66905-1
PMCID: PMC11237101

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