Article
Genetic diversity and drug resistance of HIV-1 among infected pregnant women newly diagnosed in Luanda, Angola.
PloS one - 1 Jan 2019
Sebastião Cruz S, Neto Zoraima, de Jesus Carlos S, Mirandela Marinela, Jandondo Domingos, Couto-Fernandez José C, Tanuri Amilcar, Morais Joana, Brito Miguel
Abstract excerpt
Monitoring genetic diversity and drug resistance mutations (DRMs) is critical for understanding HIV epidemiology. Here, we report HIV-1 genetic diversity and DRMs in blood samples from 42 HIV-positive pregnant women naive to antiretroviral therapy (ART), in Luanda. The samples were subjected to nested-PCR, followed by sequencing of HIV-1 pol gene, targeting the protease and reverse transcriptase fragments. HIV-1...
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