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Article

HIV-1 transmitted drug resistance in newly diagnosed individuals in Italy over the period 2015-21.

The Journal of antimicrobial chemotherapy - 3 Sept 2024

Fabeni Lavinia, Armenia Daniele, Abbate Isabella, Gagliardini Roberta, Mazzotta Valentina, Bertoli Ada, Gennari William, Forbici Federica, Berno Giulia, Piermatteo Lorenzo, Borghi Vanni, Pinnetti Carmela, Vergori Alessandra, Mondi Annalisa, Parruti Giustino, Di Sora Fiorella, Iannetta Marco, Lichtner Miriam, Latini Alessandra, Mussini Cristina, Sarmati Loredana, Perno Carlo Federico, Girardi Enrico, Antinori Andrea, Ceccherini-Silberstein Francesca, Maggi Fabrizio, Santoro Maria Mercedes

Abstract excerpt

BACKGROUND: Transmitted drug resistance (TDR) is still a critical aspect for the management of individuals living with HIV-1. Thus, its evaluation is crucial to optimize HIV care. METHODS: Overall, 2386 HIV-1 protease/reverse transcriptase and 1831 integrase sequences from drug-naïve individuals diagnosed in north and central Italy between 2015 and 2021 were analysed. TDR was evaluated over time. Phylogeny was...

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Anti-HIV Agents
Drug Resistance, Viral
HIV-1
HIV Infections

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PMID: 39028674
DOI: 10.1093/jac/dkae189
PMCID: PMC11368429

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