Article
Validation of a novel NGS based BCR::ABL1 kinase domain mutation detection assay in Indian cohort.
Scientific reports - 8 Jul 2024
Chaudhary Pooja, Chaudhary Spandan, Patel Falguni, Patel Shiv, Vaishnani Toral, Trivedi Nikha, Patel Dhiren, Sonagara Tushar, Hirapara Ashish, Vyas Kavisha, Patel Lokesh, Kumar Raja, Chakraborty Nikkan, Sharma Divya, Suthar Jigar, Kamdar Payal, Jajodia Ekta, Ahmad Firoz, Arora Neeraj
Abstract excerpt
The efficacy and treatment outcome of a CML patient are heavily dependent on BCR::ABL1 kinase domain (KD) mutation status. Next-generation sequencing technology is a bright alternative to the previously used sanger sequencing method due to its global presence in diagnostic setups, massive parallel sequencing ability, and far better sensitivity. In the present study, we have demonstrated a new protocol for kinase...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.