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Identifying antibiotic-resistant strains via cell sorting and elastic-light-scatter phenotyping.

Applied microbiology and biotechnology - 3 Jul 2024

Narayana Iyengar Sharath, Dowden Brianna, Ragheb Kathy, Patsekin Valery, Rajwa Bartek, Bae Euiwon, Robinson J Paul

Abstract excerpt

The proliferation and dissemination of antimicrobial-resistant bacteria is an increasingly global challenge and is attributed mainly to the excessive or improper use of antibiotics. Currently, the gold-standard phenotypic methodology for detecting resistant strains is agar plating, which is a time-consuming process that involves multiple subculturing steps. Genotypic analysis techniques are fast, but they require...

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PMID: 38958764
DOI: 10.1007/s00253-024-13232-0
PMCID: PMC11222266

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