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Article

ABCG2 polymorphism and rivaroxaban pharmacokinetics in healthy individuals after a single dose.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jan 2024

Santos A F Dos, Francisco Q A S, Nunes J B, Colombo F A, Boralli V B

Abstract excerpt

Rivaroxaban is a direct factor Xa inhibitor. Its interindividual variability is large and may be connected to the occurrence of adverse drug reactions or drug inefficacy. Pharmacogenetics studies concentrating on the reasons underlying rivaroxaban's inadequate response could help explain the differences in treatment results and medication safety profiles. Against this background, this study evaluated whether...

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Identifiers

PMID: 38958362
DOI: 10.1590/1414-431X2024e13257
PMCID: PMC11221861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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