Article
A Study on Associations of Long Noncoding RNA HOTAIR Polymorphisms With Genetic Susceptibility to Chronic Kidney Disease.
Journal of clinical laboratory analysis - 1 Jun 2024
Majidpour Mahdi, Saravani Ramin, Sargazi Saman, Sargazi Sara, Harati-Sadegh Mahdiyeh, Khorrami Shadi, Sarhadi Mohammad, Alidadi Ali
Abstract excerpt
BACKGROUND: The importance of long noncoding RNAs (lncRNAs) in various biological processes has been increasingly recognized in recent years. This study investigated how gene polymorphism in HOX transcript antisense RNA (HOTAIR) lncRNA affects the predisposition to chronic kidney disease (CKD). METHODS: This study comprised 150 patients with CKD and 150 healthy controls. A PCR-RFLP and ARMS-PCR techniques were...
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