Article
Tagging large CNV blocks in wheat boosts digitalization of germplasm resources by ultra-low-coverage sequencing.
Genome biology - 1 Jul 2024
Niu Jianxia, Wang Wenxi, Wang Zihao, Chen Zhe, Zhang Xiaoyu, Qin Zhen, Miao Lingfeng, Yang Zhengzhao, Xie Chaojie, Xin Mingming, Peng Huiru, Yao Yingyin, Liu Jie, Ni Zhongfu, Sun Qixin, Guo Weilong
Abstract excerpt
BACKGROUND: The massive structural variations and frequent introgression highly contribute to the genetic diversity of wheat, while the huge and complex genome of polyploid wheat hinders efficient genotyping of abundant varieties towards accurate identification, management, and exploitation of germplasm resources. RESULTS: We develop a novel workflow that identifies 1240 high-quality large copy number variation...
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