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Article

Genomic alteration discordance in the paired primary-recurrent ovarian cancers: based on the comprehensive genomic profiling (CGP) analysis.

Journal of ovarian research - 27 Jun 2024

Dong Jiayin, Ni Jing, Chen Jiahui, Wang Xuening, Ye Luxin, Xu Xia, Guo Wenwen, Chen Xiaoxiang

Abstract excerpt

PURPOSE: Ovarian cancer (OC) is characterized by a high recurrence rate, and homologous recombination deficiency (HRD) is an important biomarker in the clinical management of OC. We investigated the differences in clinical genomic profiles between the primary and platinum-sensitive recurrent OC (PSROC), focusing on HRD status. MATERIALS AND METHODS: A total of 40 formalin-fixed paraffin-embedded (FFPE) tissues of...

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Identifiers

PMID: 38937827
DOI: 10.1186/s13048-024-01455-8
PMCID: PMC11212203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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