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Article

GRA47 is important for the morphology and permeability of the parasitophorous vacuole in Toxoplasma gondii

25 Jun 2024

Abstract excerpt

Establishing an intact intracellular parasitophorous vacuole (PV) that enables efficient nutrient uptake and protein trafficking is essential for the survival and proliferation of Toxoplasma gondii. Although the PV membrane (PVM)-localized dense granule protein 17 (GRA17) and GRA23 mediate the permeability of the PVM to small molecules, including nutrient uptake and excretion of metabolic by-products, the...

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PMID: 38936501
DOI: 10.1016/j.ijpara.2024.06.003

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