Article
Multiplex Intraoperative Rapid Immunohistochemistry with Noncontact Antibody Mixing for Distinguishing the Histologic Phenotype of Lung Cancer.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2024
Kuriyama Shoji, Imai Kazuhiro, Nanjo Hiroshi, Wakamatsu Yuki, Takashima Shinogu, Matsuo Tsubasa, Iwai Hidenobu, Demura Ryo, Suzuki Haruka, Harata Yuzu, Shibano Sumire, Wakita Akiyuki, Sato Yusuke, Nomura Kyoko, Minamiya Yoshihiro
Abstract excerpt
INTRODUCTION: Determining a surgical strategy for early-stage lung cancer requires an accurate histologic diagnosis. Immunohistochemistry (IHC) enables reliable diagnosis of histological types but requires more time and more tumor tissue slides than hematoxylin and eosin staining. We aimed to assess the clinical validity of a new rapid multiplex IHC technique utilizing alternating current (AC) mixing for...
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