Article
Association between ZASP/LDB3 Pro26Ser and Inclusion Body Myopathy.
International journal of molecular sciences - 14 Jun 2024
Piga Daniela, Zanotti Simona, Ripolone Michela, Napoli Laura, Ciscato Patrizia, Gibertini Sara, Maggi Lorenzo, Fortunato Francesco, Rigamonti Andrea, Ronchi Dario, Comi Giacomo Pietro, Corti Stefania, Sciacco Monica
Abstract excerpt
Inclusion body myositis (IBM) is a slowly progressive disorder belonging to the idiopathic inflammatory myopathies, and it represents the most common adult-onset acquired myopathy. The main clinical features include proximal or distal muscular asymmetric weakness, with major involvement of long finger flexors and knee extensors. The main histological findings are the presence of fiber infiltrations, rimmed...
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