Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and functional studies of a missense variant in a glutamate transporter, SLC1A3, in Tourette syndrome.

Psychiatric genetics - 1 Apr 2011

Adamczyk Abby, Gause Colin D, Sattler Rita, Vidensky Svetlana, Rothstein Jeffery D, Singer Harvey, Wang Tao

Abstract excerpt

OBJECTIVE: Abnormalities in neurotransmission within the cortico-striatal-thalamo-cortical circuitry are implicated in the pathogenesis of Tourette syndrome. Glutamate is a major excitatory neurotransmitter and an important member in the cortico-striatal-thalamo-cortical circuitry. To explore the role of glutamatergic neurotransmission in genetic susceptibility of Tourette syndrome, we carried out the genetic and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Behavior
Share to Conserved Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoresis, Capillary

Share to Excitatory Amino Acid Transporter 1

Share to Glutamic Acid

Share to Polymorphism, Single-Stranded Conformational

Share to Subcellular Fractions

Share to Tourette Syndrome

Source

Identifiers

PMID: 21233784
DOI: 10.1097/YPG.0b013e328341a307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and functional studies of a missense variant in a glutamate transporter, SLC1A3, in Tourette syndrome.PMID 21233784Read ↗

A family based study implicates solute carrier family 1-member 3 (SLC1A3) gene in attention-deficit/hyperactivity disorder.Semantic proximity Read ↗

Duplications of SLC1A3: Associated with ADHD and autism.Semantic proximity Read ↗

Neuropsychiatric disease-associated genetic variants of the dopamine transporter display heterogeneous molecular phenotypes.Semantic proximity Read ↗

Late-onset episodic ataxia associated with SLC1A3 mutation.Semantic proximity Read ↗

Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures.Semantic proximity Read ↗

Resequencing and association study of vesicular glutamate transporter 1 gene (VGLUT1) with schizophrenia.Semantic proximity Read ↗

Impaired K+ binding to glial glutamate transporter EAAT1 in migraine.Semantic proximity Read ↗

Identification of Polymorphisms in EAAT1 Glutamate Transporter Gene SLC1A3 Associated with Reduced Migraine Risk.Semantic proximity Read ↗

The c.824C>A and c.616dupA mutations in the SLC17a8 gene are associated with auditory neuropathy and lead to defective expression of VGluT3.Semantic proximity Read ↗

Association of SNPs linked to increased expression of SLC1A1 with schizophrenia.Semantic proximity Read ↗

Homozygous SLC6A17 mutations cause autosomal-recessive intellectual disability with progressive tremor, speech impairment, and behavioral problems.Semantic proximity Read ↗

Identification of rare high-risk copy number variants affecting the dopamine transporter gene in mental disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.