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Article

Application of Graph Models to the Identification of Transcriptomic Oncometabolic Pathways in Human Hepatocellular Carcinoma.

Biomolecules - 3 Jun 2024

Barace Sergio, Santamaría Eva, Infante Stefany, Arcelus Sara, De La Fuente Jesus, Goñi Enrique, Tamayo Ibon, Ochoa Idoia, Sogbe Miguel, Sangro Bruno, Hernaez Mikel, Avila Matias A, Argemi Josepmaria

Abstract excerpt

Whole-tissue transcriptomic analyses have been helpful to characterize molecular subtypes of hepatocellular carcinoma (HCC). Metabolic subtypes of human HCC have been defined, yet whether these different metabolic classes are clinically relevant or derive in actionable cancer vulnerabilities is still an unanswered question. Publicly available gene sets or gene signatures have been used to infer functional changes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38927057
DOI: 10.3390/biom14060653
PMCID: PMC11201933

Genes

CTNNB1
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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