Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-cell RNA sequencing of human oocytes reveals a differential transcriptomic profile associated with agar-like zona pellucida

26 Jun 2024

Abstract excerpt

BACKGROUND: Agar-like zona pellucida (ZP) is the most common type of abnormal ZP, and is one of the causes of low fertility or infertility. However, the molecular mechanism of agar-like ZP is unclear. Single-cell RNA-sequencing (scRNA-seq) analysis was used to assess the cellular and molecular landscape of oocytes with agar-like ZP. METHODS: Human metaphase I (MI) oocytes were collected from four patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Preterm Birth and Chorioamnionitis
Share to Reproductive Biology and Fertility
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38926883
DOI: 10.1186/s13048-024-01463-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell RNA sequencing of human oocytes reveals a differential transcriptomic profile associated with agar-like zona pellucidaPMID 38926883Read ↗

Embryological Characteristics of Human Oocytes With Agar-Like Zona Pellucida and Its Clinical Treatment StrategySemantic proximity Read ↗

Identification of zona pellucida defects revealed a novel loss-of-function mutation in ZP2 in humans and rats.Semantic proximity Read ↗

Single-cell RNA sequencing of oocytes from ovarian endometriosis patients reveals a differential transcriptomic profile associated with lower qualitySemantic proximity Read ↗

Heterozygous mutations in ZP1 and ZP3 cause formation disorder of ZP and female infertility in human.Semantic proximity Read ↗

Transcriptome Landscape of Human Oocytes and Granulosa Cells Throughout FolliculogenesisSemantic proximity Read ↗

Zona Pellucida Genes and Proteins: Essential Players in Mammalian Oogenesis and FertilitySemantic proximity Read ↗

Single-Cell Transcriptomics Analysis of Human Small Antral FolliclesSemantic proximity Read ↗

Single-cell proteomics analysis of human oocytes during GV-to-MI transitionSemantic proximity Read ↗

Single-cell RNA-seq identified novel genes involved in primordial follicle formationSemantic proximity Read ↗

Transcriptomic analysis and epigenetic regulators in human oocytes at different stages of oocyte meiotic maturationSemantic proximity Read ↗

Recent Advances in Understandings Towards Pathogenesis and Treatment for Intrauterine Adhesion and Disruptive Insights from Single-Cell AnalysisSemantic proximity Read ↗

The human cumulus–oocyte complex gene-expression profileSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.