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Redirecting electron flow in Acetobacterium woodii enables growth on CO and improves growth on formate.

Nature communications - 26 Jun 2024

Moon Jimyung, Poehlein Anja, Daniel Rolf, Müller Volker

Abstract excerpt

Anaerobic, acetogenic bacteria are well known for their ability to convert various one-carbon compounds, promising feedstocks for a future, sustainable biotechnology, to products such as acetate and biofuels. The model acetogen Acetobacterium woodii can grow on CO2, formate or methanol, but not on carbon monoxide, an important industrial waste product. Since hydrogenases are targets of CO inhibition, here, we...

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Acetates
Bacterial Proteins
Biomass
Carbon Dioxide
Carbon Monoxide

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PMID: 38926344
DOI: 10.1038/s41467-024-49680-5
PMCID: PMC11208171

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