[DNA aneuploidy in children with acute leukemia: II. Correlation with the phenotype of blasts, clinical picture and course of disease].

doi:10.1055/s-2008-1033972

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Article

[DNA aneuploidy in children with acute leukemia: II. Correlation with the phenotype of blasts, clinical picture and course of disease].

Klinische Padiatrie - 1 Jan 2000

Ritter J, Hiddemann W, Wörmann B, Büchner T, Schellong G

Abstract excerpt

Analysis of the cellular DNA content was carried out in 162 children with ALL and 34 children with AML admitted to the university children's hospital Münster between 1979 and 1984. DNA aneuploidies were identified at a similar frequency in ALL (40%) and AML (44%). However, the degree of DNA aneuploidies (DNA-index) was significantly lower in aneuploid AML (median 1.09) than in aneuploid ALL (median 1.19). We...

Topics

Acid Phosphatase
Aneuploidy
Antineoplastic Combined Chemotherapy Protocols
Child
Clinical Trials as Topic
DNA, Neoplasm
Flow Cytometry
Humans
L-Lactate Dehydrogenase
Leukemia, Lymphoid
Leukemia, Myeloid, Acute

Leukocyte Count

Phenotype

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