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Article

Impact of whole-genome duplications on structural variant evolution in Cochlearia.

Nature communications - 25 Jun 2024

Hämälä Tuomas, Moore Christopher, Cowan Laura, Carlile Matthew, Gopaulchan David, Brandrud Marie K, Birkeland Siri, Loose Matthew, Kolář Filip, Koch Marcus A, Yant Levi

Abstract excerpt

Polyploidy, the result of whole-genome duplication (WGD), is a major driver of eukaryote evolution. Yet WGDs are hugely disruptive mutations, and we still lack a clear understanding of their fitness consequences. Here, we study whether WGDs result in greater diversity of genomic structural variants (SVs) and how they influence evolutionary dynamics in a plant genus, Cochlearia (Brassicaceae). By using long-read...

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Source

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Identifiers

PMID: 38918389
DOI: 10.1038/s41467-024-49679-y
PMCID: PMC11199601

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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