Article
Causal relationship between basal metabolic rate and intervertebral disc degeneration: a Mendelian randomization study.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society - 1 Sept 2024
Liu Zhengqiang, Cai Huili, Zhou Zhenyu, Chen Shiwen, Yang Diao, Zhuo Can, Chen Haidan
Abstract excerpt
BACKGROUND: The role of basal metabolic rate (BMR) in intervertebral disc degeneration (IVDD) is still uncertain. To address this gap, we conducted a Mendelian randomization (MR) study to comprehensively explore the causal relationship between BMR and IVDD. METHODS: BMR data were obtained from a large genome-wide association study (GWAS) database, while IVDD data were derived from the FinnGen project. The causal...
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